产品货号：
GS4673
中文名称：
重组人Midkine
英文名称：
Recombinant Human Midkine
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 13.4kDa,a single non-glycosylated polypeptide chain containing 123 amino acids.
储存条件：冷冻（-20℃）
概述
Midkine,also named MK,MK1,NEGF 2,is belonging to the neurotrophic and developmentally-regulated heparin-binding molecules family.It is encoded by the MDK gene.The Midkine protein includes five intrachain disulfide bonds which hold two domains and there are three antiparallel beta-sheets in each domain.A chondroitin sulfate proteoglycan,protein-tyrosine phosphatase zeta(PTPzeta),is a receptor for MK.MK promotes the growth,survival,and migration of various cells,and plays roles in neurogenesis and epithelial mesenchymal interactions during organogenesis.The predicted molecular weight is approximately 13.3 kDa,based on a mature peptide length of 118 amino acid residues in the mouse and 121 amino acid residues in the human.Across species,MK shows 87%identity between the human and murine proteins.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人Midkine，Midkine, Human，Recombinant Human Midkine
储存条件：冷冻（-20℃）
概述
Midkine,also named MK,MK1,NEGF 2,is belonging to the neurotrophic and developmentally-regulated heparin-binding molecules family.It is encoded by the MDK gene.The Midkine protein includes five intrachain disulfide bonds which hold two domains and there are three antiparallel beta-sheets in each domain.A chondroitin sulfate proteoglycan,protein-tyrosine phosphatase zeta(PTPzeta),is a receptor for MK.MK promotes the growth,survival,and migration of various cells,and plays roles in neurogenesis and epithelial mesenchymal interactions during organogenesis.The predicted molecular weight is approximately 13.3 kDa,based on a mature peptide length of 118 amino acid residues in the mouse and 121 amino acid residues in the human.Across species,MK shows 87%identity between the human and murine proteins.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 0.1-10ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH7.4. |
| 内毒素 | Less than 1 EU/μg of rHuMidkine as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | VAKKKDKVKK GGPGSECAEW AWGPCTPSSK DCGVGFREGT CGAQTQRIRC RVPCNWKKEF GADCKYKFEN WGACDGGTGT KVRQGTLKKA RYNAQCQETI RVTKPCTPKT KAKAKAKKGK GKD |
相关搜索：重组人Midkine，Midkine, Human，Recombinant Human Midkine